⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814733 | 0.77 | CYP3A4 (0.37) | — | |
| SCHEMBL1974135 | 0.74 | ALDH1A1 (0.37) | — | |
| SCHEMBL27448231 | 0.72 | ALDH1A1 (0.36) | — | |
| SCHEMBL1971485 | 0.72 | OPRM1 (0.44) | — | |
| SCHEMBL28361753 | 0.70 | OPRM1 (0.42) | — | |
| SCHEMBL28277593 | 0.70 | OPRM1 (0.42) | — | |
| SCHEMBL28153724 | 0.70 | OPRM1 (0.42) | — | |
| SCHEMBL1968956 | 0.70 | OPRM1 (0.42) | — | |
| SCHEMBL28271638 | 0.70 | OPRM1 (0.42) | — | |
| SCHEMBL28154751 | 0.70 | OPRM1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008028-B | Pyrimidine derivative for inhibiting growth of cancer cells and medical application thereof | 昂科比克斯有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-114746432-B | Transition metal compound, catalyst composition comprising the same, and process for producing olefin polymer using the catalyst composition | 沙特基础工业爱思开NEXLENE私人有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117881678-A | Compound with SHP2 protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117700420-A | Fused tetracyclic compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117597341-A | Sulfonamide derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117597352-A | Method for producing micrococcum-based carboxylic acid compound and micrococcum-based carboxylic acid compound produced thereby | A&J科学有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117229284-A | Tricyclic fused heterocyclic compound, preparation method and application thereof in medicine | 上海泽德曼医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116785449-A | Benzopyrrolopyrrole heterocyclic compound and conjugate thereof, preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116685323-A | Purinone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-113929618-B | Oxo-pyridine amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2005035500-A2 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-04-21 | — | — | WO | disclosed |
| US-6864261-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2005-03-08 | — | — | US | disclosed |
| WO-2005019353-A2 | COPOLYMER SURFACTANTS | COLUMBIA INSURANCE COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050039635-A1 | Copolymer surfactants | BENJAMIN MOORE & CO. | 2005-02-24 | — | — | US | disclosed |
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | APPLIED BIOSYSTEMS, LLC | 2005-02-03 | — | — | US | disclosed |
| WO-2004104054-A1 | POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-12-02 | — | — | WO | disclosed |
| US-20040127501-A1 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2004-07-01 | — | — | US | disclosed |
| WO-2004029044-A1 | PYRIMIDINE COMPOUNDS AS THERAPEUTIC AGENTS | EURO-CELTIQUE, S.A. (LU) | 2004-04-08 | — | — | WO | disclosed |
| US-20040053914-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2004-03-18 | — | — | US | disclosed |
| WO-2003093236-A1 | 1-(PYRID-2-YL)-PIPERAZINE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR INHIBITOR | EURO-CELTIQUE, S.A. (LU) | 2003-11-13 | — | — | WO | disclosed |