Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28105635 | 0.91 | LMNA (0.36) | CYP3A4MEN1ALOX15KMT2ALMNA | |
| SCHEMBL5872378 | 0.88 | MEN1 (0.41) | CYP3A4MEN1ALOX15KMT2ALMNA | |
| SCHEMBL24296723 | 0.82 | ALDH1A1 (0.41) | CYP3A4MEN1ALOX15KMT2A | |
| SCHEMBL19142935 | 0.78 | MEN1 (0.32) | CYP3A4MEN1ALOX15KMT2ALMNA | |
| SCHEMBL29163241 | 0.78 | OPRM1 (0.38) | LMNATSHR | |
| SCHEMBL2563360 | 0.78 | TSHR (0.33) | LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL598167 | 0.77 | TSHR (0.40) | LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL10814728 | 0.77 | MEN1 (0.38) | CYP3A4MEN1ALOX15KMT2ALMNA | |
| SCHEMBL305352 | 0.77 | — | — | |
| SCHEMBL21044806 | 0.76 | SMN1; SMN2 (0.46) | MEN1KMT2ALMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129211-B1 | 2,6-TRANS-DIMETHYL MORPHOLINE DERIVATIVES, FUNGICIDES CONTAINING THEM AND METHODS OF COMBATING FUNGI | BASF Aktiengesellschaft (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0129211-A1 | 2,6-Trans-dimethyl morpholine derivatives, fungicides containing them and methods of combating fungi | BASF Aktiengesellschaft (DE) | 1984-12-27 | — | — | EP | disclosed |