Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512834 | 1.00 | MEN1 (0.41) | MEN1KMT2AGRM6GPR84MAPK1 | |
| SCHEMBL28086772 | 0.86 | MAOA (0.41) | MEN1KMT2AGRM6MAPK1EPHX2 | |
| SCHEMBL7911204 | 0.82 | CA12 (0.50) | GPR84ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL31090834 | 0.82 | CA12 (0.50) | GPR84ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL28858961 | 0.80 | KDM4E (0.37) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10067761 | 0.80 | KMT2A (0.37) | MEN1KMT2AGPR84MAPK1ALDH1A1 | |
| SCHEMBL7712683 | 0.78 | TSHR (0.47) | MEN1KMT2AMAPK1ALDH1A1KDM4E | |
| SCHEMBL29433567 | 0.78 | TSHR (0.47) | MEN1KMT2AMAPK1ALDH1A1KDM4E | |
| SCHEMBL8344638 | 0.76 | MAOB (0.40) | MEN1KMT2AGPR84ALDH1A1KDM4E | |
| SCHEMBL22992559 | 0.76 | ALOX5 (0.57) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767106-B | Oxazaquinazolin-7 (8H) -ones, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112390818-B | Substituted heteroaromatic dihydro pyrimidinone derivatives, their preparation and pharmaceutical use | 劲方医药科技(上海)有限公司 | 2023-08-22 | — | — | CN | disclosed |