Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544867 | 0.91 | SCN9A (0.43) | MMP2MMP9FOLH1MDM2CA1 | |
| SCHEMBL30544869 | 0.80 | FOLH1 (0.42) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL30544861 | 0.77 | MMP2 (0.46) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL34467689 | 0.76 | ALB (0.46) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30544859 | 0.73 | FOLH1 (0.47) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL30544860 | 0.73 | FOLH1 (0.47) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL10615102 | 0.72 | GRIN1 (0.55) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL31300250 | 0.71 | KMT2A (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL607885 | 0.70 | ITGB3 (0.60) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL607886 | 0.70 | ITGB3 (0.60) | MMP2MMP9FOLH1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496837-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | The Research Foundation for The State University of New York (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023178107-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-09-21 | — | — | WO | disclosed |