SCHEMBL607886

SCHEMBL607886

NCCCC[C@H](NC(=O)c1ccccc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.60
ITGA2B P08514 1/20 0.60
ERAP2 Q6P179 4/20 0.56
LNPEP Q9UIQ6 4/20 0.56
ERAP1 Q9NZ08 2/20 0.55
HPGDS O60760 1/20 0.54
C3AR1 Q16581 1/20 0.54
CTSB P07858 1/20 0.54
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
GRIN1 Q05586 1/20 0.53
GRIN2A Q12879 1/20 0.53
CA2 P00918 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA9 Q16790 1/20 0.53
FOLH1 Q04609 1/20 0.53
PDE4A P27815 3/20 0.50
PDE4B Q07343 2/20 0.50
PDE4C Q08493 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607885 1.00 ITGB3 (0.60) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL1980150 0.95 ITGB3 (0.57) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL8847374 0.95 ITGB3 (0.57) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL1980652 0.95 ITGB3 (0.57) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL22312697 0.94 ITGB3 (0.55) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL7390292 0.94 ITGB3 (0.55) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL6810961 0.94 ITGB3 (0.55) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL6810906 0.93 HPGDS (0.64) ITGB3ITGA2BERAP2LNPEPERAP1
Octadecylamine SCHEMBL7750304 0.92 CA2 (0.58) ITGB3ITGA2BERAP2LNPEPERAP1
SCHEMBL10374327 0.89 LNPEP (0.53) ITGB3ITGA2BERAP2LNPEPERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120040915-A1 PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-02-16 US claimed
WO-2010088527-A2 PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2010-08-05 WO claimed
US-20040062773-A1 Compositions for the delivery of antigens EMISPHERE TECHNOLOGIES INC. 2004-04-01 US claimed
EP-0784469-B1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 2004-03-24 EP claimed
US-6610329-B2 Using acylated amino acid as carrier EMISPHERE TECHNOLOGIES INC. 2003-08-26 US claimed
US-20020001591-A1 Compositions for the delivery of antigens EMISPHERE TECHNOLOGIES, INC. 2002-01-03 US claimed
US-5958457-A MIXTURES OF ANTIGENS WITH ADJUVANTS AND ACYLATED AMINO ACIDS OR SALTS, POLYMERS OR SULFONATED AMINO ACIDS EMISPHERE TECHNOLOGIES, INC. (US) 1999-09-28 US claimed
EP-0784469-A4 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 1999-03-24 EP claimed
EP-0784469-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS Emisphere Technologies, Inc. (US) 1997-07-23 EP claimed
WO-1996012474-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECHNOLOGIES, INC. (US) 1996-05-02 WO claimed
EP-0367514-A2 Human leukocyte elastase inhibitors and methods for producing and using same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1990-05-09 EP claimed
WO-2024211633-A1 POLYPEPTIDE ADJUVANTS AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-10-10 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-118515908-A Modified polyurethane environment-friendly sponge and preparation method thereof 伟建实业(苏州)有限公司 2024-08-20 CN disclosed
CN-117618533-B Photosensitive curing spray and preparation method and application thereof 上海市第四人民医院 2024-08-06 CN disclosed
WO-1989009786-A1 PEPTIDE DERIVATIVES SANDOZ AG (CH) 1989-10-19 WO disclosed
WO-1989001944-A1 EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1989-03-09 WO disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP disclosed
EP-0119954-A2 3-Amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use CIBA-GEIGY AG (CH) 1984-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020001591-A1 Compositions for the delivery of antigens CD47, CD74, LY96 ITGB3 972/4885ITGA2B 655/4885ERAP2 628/4885
US-20040062773-A1 Compositions for the delivery of antigens CD47, CD74, LY96 ITGB3 972/4885ITGA2B 655/4885ERAP2 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.