Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544866 | 0.85 | FOLH1 (0.37) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL30544862 | 0.82 | FOLH1 (0.36) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL30544854 | 0.77 | FOLH1 (0.51) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL30544857 | 0.77 | MMP2 (0.46) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL34467664 | 0.76 | NOS1 (0.41) | DAGLA | |
| SCHEMBL10615102 | 0.72 | GRIN1 (0.55) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL31300267 | 0.72 | NOS1 (0.43) | DAGLA | |
| SCHEMBL607885 | 0.70 | ITGB3 (0.60) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL607886 | 0.70 | ITGB3 (0.60) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL6810906 | 0.70 | HPGDS (0.64) | MMP2MMP9FOLH1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496837-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | The Research Foundation for The State University of New York (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023178107-A2 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-09-21 | — | — | WO | disclosed |