Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475416 | 1.00 | CNR2 (0.42) | CNR2ATMKDM4EALDH1A1SLC7A5 | |
| SCHEMBL1814092 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL3622568 | 0.85 | LPL (0.41) | ATMKDM4EALDH1A1CA1CA2 | |
| SCHEMBL30242746 | 0.85 | CA1 (0.56) | CNR2KDM4EALDH1A1CA1CA2 | |
| SCHEMBL2032625 | 0.85 | CA1 (0.56) | CNR2KDM4EALDH1A1CA1CA2 | |
| SCHEMBL21817189 | 0.84 | CYP4A11 (0.38) | KDM4EALDH1A1SLC7A5CA1CA2 | |
| SCHEMBL10209953 | 0.84 | ATAD2 (0.42) | CNR2ATMKDM4EALDH1A1CA1 | |
| SCHEMBL310685 | 0.84 | NOTUM (0.47) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL1437728 | 0.84 | ALDH1A1 (0.41) | CNR2ATMKDM4EALDH1A1CA1 | |
| SCHEMBL16861683 | 0.84 | ALDH1A1 (0.42) | ATMKDM4EALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499609-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023192817-A9 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2024-10-03 | — | — | WO | disclosed |
| WO-2023192817-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |