SCHEMBL1814092

SCHEMBL1814092

COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cc(C(=O)OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
ALDH1A1 P00352 4/20 0.44
CA1 P00915 5/20 0.44
CA2 P00918 5/20 0.44
CA9 Q16790 5/20 0.44
CA12 O43570 3/20 0.44
CA7 P43166 3/20 0.44
CA14 Q9ULX7 3/20 0.44
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.43
XDH P47989 2/20 0.43
GAA P10253 1/20 0.43
NFKB1 P19838 1/20 0.43
GFER P55789 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
FUT7 Q11130 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
DGAT1 O75907 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8444503 0.92 KDM4E (0.39) KDM4EALDH1A1CA1CA2CA9
SCHEMBL2032625 0.91 CA1 (0.56) KDM4EALDH1A1CA1CA2CA9
SCHEMBL30545643 0.91 CNR2 (0.42) KDM4EALDH1A1CA1CA2CA9
SCHEMBL30242746 0.91 CA1 (0.56) KDM4EALDH1A1CA1CA2CA9
SCHEMBL7475416 0.91 CNR2 (0.42) KDM4EALDH1A1CA1CA2CA9
SCHEMBL3622568 0.91 LPL (0.41) KDM4EALDH1A1CA1CA2CA9
SCHEMBL1437728 0.89 ALDH1A1 (0.41) KDM4EALDH1A1CA1CA2CA9
SCHEMBL310685 0.89 NOTUM (0.47) KDM4EALDH1A1CA1CA2CA9
SCHEMBL10209953 0.89 ATAD2 (0.42) KDM4EALDH1A1CA1CA2CA9
SCHEMBL14781024 0.89 KDM4E (0.39) KDM4EALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894221-B Water-soluble jacobs aromatic compound and preparation method thereof 平顶山学院 2025-05-30 CN claimed
CN-118684558-B Pesticide intermediate and method for synthesizing pesticide intermediate by using coal industrial phenol 中煤鄂尔多斯能源化工有限公司 2024-11-05 CN claimed
CN-118307822-B Production process of environment-friendly laminating material 广东美士达药包材料股份有限公司 2024-10-18 CN claimed
CN-118684558-A Pesticide intermediate and method for synthesizing pesticide intermediate by using coal industrial phenol 中煤鄂尔多斯能源化工有限公司 2024-09-24 CN claimed
CN-118307822-A Production process of environment-friendly laminating material 广东美士达药包材料股份有限公司 2024-07-09 CN claimed
CN-115894221-A Water-soluble Bernoulli aromatic compound and preparation method thereof 平顶山学院 2023-04-04 CN claimed
CN-115433364-A Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof 中国科学院福建物质结构研究所 2022-12-06 CN claimed
CN-115894221-B Water-soluble jacobs aromatic compound and preparation method thereof 平顶山学院 2025-05-30 CN disclosed
CN-118684558-B Pesticide intermediate and method for synthesizing pesticide intermediate by using coal industrial phenol 中煤鄂尔多斯能源化工有限公司 2024-11-05 CN disclosed
EP-4452987-A1 SYNTHESIS OF METAL ORGANIC FRAMEWORK (MOF) MATERIALS WITH HIGH ADSORPTION CAPACITY OF ORGANIC COMPOUNDS AND CO2 CAPTURE Université de Strasbourg (FR) 2024-10-30 EP disclosed
CN-118307822-B Production process of environment-friendly laminating material 广东美士达药包材料股份有限公司 2024-10-18 CN disclosed
CN-118684558-A Pesticide intermediate and method for synthesizing pesticide intermediate by using coal industrial phenol 中煤鄂尔多斯能源化工有限公司 2024-09-24 CN disclosed
CN-118307822-A Production process of environment-friendly laminating material 广东美士达药包材料股份有限公司 2024-07-09 CN disclosed
WO-2019157013-A1 COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF HYDROCARBON ISOMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-08-15 WO disclosed
US-20170173559-A1 A POROUS METAL-ORGANIC FRAMEWORK WITH PYRIMIDINE GROUPS FOR METHANE STORAGE EXHIBITING HIGH WORKING CAPACITY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2017-06-22 US disclosed
EP-2494408-B9 PHOTOCHROMIC MATERIALS TRANSITIONS OPTICAL INC (US) 2015-09-02 EP disclosed
EP-2494408-B1 PHOTOCHROMIC MATERIALS TRANSITIONS OPTICAL INC (US) 2015-04-15 EP disclosed
US-8518305-B2 Photochromic materials TRANSITIONS OPTICAL, INC. (US) 2013-08-27 US disclosed
US-20110108781-A1 PHOTOCHROMIC MATERIALS TRANSITIONS OPTICAL, INC. (US) 2011-05-12 US disclosed
WO-2010069504-A1 (3-OXO)PYRIDIN-4-YLUREA DERIVATIVES AS PDE4 INHIBITORS ALMIRALL, S.A. (ES) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110108781-A1 PHOTOCHROMIC MATERIALS INCENP, SMCHD1, NEDD8 KDM4E 931/4885ALDH1A1 229/4885CA1 867/4885
US-20170173559-A1 A POROUS METAL-ORGANIC FRAMEWORK WITH PYRIMIDINE GROUPS FOR METHANE STORAGE EXHIBITING HIGH WORKING CAPACITY MTHFD1, MRPS9, YTHDF2 KDM4E 1203/4885ALDH1A1 1670/4885CA1 1921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.