Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1003649 | 1.00 | CYP1A2 (0.50) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL1258663 | 0.99 | POLB (0.51) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL11689863 | 0.95 | MAPT (0.48) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL14364056 | 0.86 | POLB (0.55) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| Hydrochloric Acid SCHEMBL7553008 | 0.84 | TP53 (0.51) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL14588703 | 0.82 | MEN1 (0.56) | CYP1A2MAPTCYP2C9CYP2C19HPGD | |
| SCHEMBL3445622 | 0.78 | MAPT (0.62) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL13788773 | 0.78 | MAPT (0.58) | CYP1A2MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL9362200 | 0.78 | HDAC1 (0.68) | MAPTHDAC1HDAC8HDAC6TP53 | |
| SCHEMBL20123332 | 0.76 | POLB (0.53) | CYP1A2MAPTCYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117223679-B | Transgenic animal model and construction method and application thereof | 中国科学院深圳先进技术研究院 | 2026-05-15 | — | — | CN | disclosed |
| CN-113729231-B | Composition for improving cartilage function | 雪印惠乳业株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-118126944-A | Method for inducing directional differentiation of rabbit bone marrow-derived cells and application thereof | 五邑大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-113768159-B | Composition for improving cartilage function | 雪印惠乳业株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116531365-B | Application of notopterol in preparation of medicines for preventing and/or treating periodontitis | 四川大学 | 2024-03-26 | — | — | CN | disclosed |
| US-20240003922-A1 | POLYMERIC GEL COMPOSITIONS FOR DETECTION OF THC | Genesee Valley Innovations, LLC | 2024-01-04 | — | — | US | disclosed |
| CN-117223679-A | Transgenic animal model and construction method and application thereof | 中国科学院深圳先进技术研究院 | 2023-12-15 | — | — | CN | disclosed |
| CN-116531365-A | Application of notopterol in preparation of medicines for preventing and/or treating periodontitis | 四川大学 | 2023-08-04 | — | — | CN | disclosed |