SCHEMBL12440932

SCHEMBL12440932

COc1ccc(-n2c3ccc(C)cc3c3cc(Br)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.43
HTT P42858 3/20 0.43
MAPT P10636 2/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HIF1A Q16665 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TP53 P04637 2/20 0.43
POLB P06746 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ACHE P22303 1/20 0.40
KDM4E B2RXH2 1/20 0.39
CUL4A Q13619 1/20 0.39
LMNA P02545 1/20 0.39
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30952420 0.92 MAPT (0.45) HPGDHTTMAPTPKMALOX15
SCHEMBL669186 0.92 MAPT (0.45) HPGDHTTMAPTPKMALOX15
SCHEMBL3054903 0.91 HTT (0.49) HPGDHTTMAPTPKMALOX15
SCHEMBL4251581 0.89 DNM1 (0.39) HPGDHTTMAPTTSHRMAPK1
SCHEMBL2721451 0.88 ALDH1A1 (0.41) MAPTALOX15TSHRMAPK1SMN1; SMN2
SCHEMBL14845769 0.88 ALDH1A1 (0.41) HPGDHTTMAPTTSHRMAPK1
SCHEMBL5999407 0.85 MAPT (0.53) HPGDHTTMAPTPKMALOX15
SCHEMBL30018831 0.85 MAPT (0.53) HPGDHTTMAPTPKMALOX15
SCHEMBL3902452 0.84 DNM1 (0.36) MAPTTSHRMAPK1SMN1; SMN2POLB
SCHEMBL13956895 0.84 DNM1 (0.36) MAPTTSHRMAPK1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 HPGD 4663/4885HTT 3489/4885MAPT 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.