SCHEMBL3054971

SCHEMBL3054971

O=C(O)c1ccc(C(F)(F)F)n(Cc2ccccc2)c1=O

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.62
PLA2G1B P04054 1/20 0.62
ATG4B Q9Y4P1 1/20 0.62
LMNA P02545 3/20 0.61
XBP1 P17861 2/20 0.61
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
NOTUM Q6P988 3/20 0.46
POLB P06746 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MYC P01106 1/20 0.43
FABP4 P15090 3/20 0.41
CMA1 P23946 1/20 0.41
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3055051 0.90 L3MBTL1 (0.60) L3MBTL1PLA2G1BATG4BLMNAXBP1
SCHEMBL28024350 0.80 TSHR (0.50) L3MBTL1PLA2G1BATG4BLMNAXBP1
SCHEMBL5030798 0.80 LMNA (0.48) L3MBTL1PLA2G1BATG4BLMNAXBP1
SCHEMBL3051026 0.79 L3MBTL1 (0.50) L3MBTL1PLA2G1BATG4BLMNAXBP1
SCHEMBL4430834 0.77 NOTUM (0.60) L3MBTL1LMNAMEN1KMT2ANOTUM
SCHEMBL4428277 0.76 NOTUM (0.48) L3MBTL1LMNAMEN1KMT2ANOTUM
SCHEMBL3051487 0.75 LMNA (0.44) L3MBTL1PLA2G1BATG4BLMNAXBP1
SCHEMBL3050974 0.74 NOTUM (0.57) L3MBTL1LMNAXBP1MEN1KMT2A
SCHEMBL17668088 0.72 ADORA2A (0.41) L3MBTL1PLA2G1BATG4BMEN1KMT2A
SCHEMBL31339924 0.72 CCR2 (0.56) NOTUMFABP4CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1982978-B1 PYRIDONE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 2014-08-27 EP disclosed
US-8076487-B2 Pyridone derivative and herbicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2011-12-13 US disclosed
US-20100222592-A1 Pyridone Derivative and Herbicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-09-02 US disclosed
EP-1982978-A1 PYRIDONE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222592-A1 Pyridone Derivative and Herbicide PDXK, PNPO, CBR3 L3MBTL1 1113/4885PLA2G1B 2348/4885ATG4B 3134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.