Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304148 | 0.88 | JAK2 (0.33) | — | |
| SCHEMBL1922562 | 0.87 | NPY5R (0.38) | — | |
| SCHEMBL302220 | 0.86 | NPY5R (0.35) | TNIKKIT | |
| SCHEMBL305501 | 0.85 | TNIK (0.41) | TNIK | |
| SCHEMBL305998 | 0.80 | ACP1 (0.35) | — | |
| SCHEMBL305389 | 0.77 | CARM1 (0.37) | BRD4 | |
| SCHEMBL27950080 | 0.76 | TNIK (0.37) | TNIK | |
| SCHEMBL1922064 | 0.75 | METAP2 (0.32) | BRD4 | |
| SCHEMBL304707 | 0.75 | CCNT1 (0.35) | — | |
| SCHEMBL2029654 | 0.75 | ALDH1A1 (0.41) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500853-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2328871-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2011-06-08 | — | — | EP | claimed |