Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 8/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326125 | 1.00 | MALT1 (0.38) | MALT1AXLTYRO3MERTKMGLL | |
| SCHEMBL25327189 | 0.83 | LOXL2 (0.34) | MGLLLOXL2ABHD6FAAH | |
| SCHEMBL30553180 | 0.83 | LOXL2 (0.34) | MGLLLOXL2ABHD6FAAH | |
| SCHEMBL30553320 | 0.82 | GPR119 (0.35) | MGLLLOXL2ABHD6 | |
| SCHEMBL25326437 | 0.82 | GPR119 (0.35) | MGLLLOXL2ABHD6 | |
| SCHEMBL30700206 | 0.80 | MALT1 (0.35) | MALT1AXLTYRO3MERTKLOXL2 | |
| SCHEMBL25323027 | 0.80 | MGLL (0.36) | MGLLABHD6FAAH | |
| SCHEMBL25326016 | 0.80 | LOXL2 (0.33) | MGLLLOXL2ABHD6FAAH | |
| SCHEMBL30553210 | 0.80 | LOXL2 (0.33) | MGLLLOXL2ABHD6FAAH | |
| SCHEMBL25145999 | 0.78 | MGLL (0.42) | MALT1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |