Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325576 | 1.00 | FAAH (0.36) | FAAHP2RX7MGLLPDCD1LG2CD274 | |
| SCHEMBL25328280 | 0.91 | NTRK1 (0.35) | P2RX7MGLLPDCD1LG2CD274 | |
| SCHEMBL25324066 | 0.86 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL25324075 | 0.85 | P2RX7 (0.37) | P2RX7MGLLPDCD1LG2CD274 | |
| SCHEMBL25325226 | 0.85 | FAAH (0.38) | FAAHP2RX7MGLLPDCD1LG2CD274 | |
| SCHEMBL25323130 | 0.84 | PDE2A (0.37) | P2RX7MGLL | |
| SCHEMBL25322265 | 0.84 | POLB (0.39) | MGLL | |
| SCHEMBL25325835 | 0.82 | MGLL (0.37) | MGLL | |
| SCHEMBL25324202 | 0.82 | FAAH (0.38) | FAAHMGLL | |
| SCHEMBL30553134 | 0.82 | FAAH (0.38) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |