Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24449959 | 1.00 | RORC (0.41) | RORCPIK3R1PIK3CAP2RX3P2RX2 | |
| SCHEMBL29527631 | 0.85 | RORC (0.53) | RORCPIK3R1PIK3CAP2RX3P2RX2 | |
| SCHEMBL22959151 | 0.85 | RORC (0.53) | RORCPIK3R1PIK3CAP2RX3P2RX2 | |
| SCHEMBL24449305 | 0.85 | RORC (0.41) | RORCPIK3R1PIK3CAP2RX3P2RX2 | |
| SCHEMBL24449302 | 0.81 | RORC (0.41) | RORCTHRBTHRAGAAMAPT | |
| SCHEMBL24449964 | 0.80 | RORC (0.46) | RORCPIK3R1PIK3CAP2RX3P2RX2 | |
| SCHEMBL22959236 | 0.76 | RORC (0.47) | RORCP2RX3P2RX2THRBMAPT | |
| SCHEMBL115578 | 0.75 | PIK3R1 (0.40) | PIK3R1PIK3CAP2RX3P2RX2POLB | |
| SCHEMBL282017 | 0.74 | THRB (0.53) | RORCP2RX3P2RX2THRBTHRA | |
| SCHEMBL29066191 | 0.74 | THRB (0.41) | PIK3R1PIK3CAP2RX3P2RX2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |