Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 20/20 | 0.63 |
| ▸ | THRA | P10827 | 6/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24407975 | 0.84 | THRB (0.70) | THRBTHRA | |
| SCHEMBL3532385 | 0.82 | THRB (0.70) | THRBTHRA | |
| SCHEMBL24407921 | 0.82 | THRB (0.65) | THRBTHRA | |
| SCHEMBL29526892 | 0.80 | THRB (0.41) | THRBTHRA | |
| SCHEMBL29066254 | 0.79 | THRA (0.74) | THRBTHRA | |
| SCHEMBL29066203 | 0.79 | THRA (0.67) | THRBTHRA | |
| SCHEMBL23168581 | 0.78 | THRB (0.56) | THRBTHRA | |
| SCHEMBL2924045 | 0.77 | THRA (1.00) | THRBTHRA | |
| SCHEMBL6219582 | 0.77 | NPBWR1 (0.59) | THRBTHRA | |
| SCHEMBL6217716 | 0.76 | THRB (0.67) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |