Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25679309 | 1.00 | CXCL8 (0.53) | CXCL8AKR1B1TDP1PTGS2ABCB11 | |
| SCHEMBL31033368 | 0.81 | FFAR1 (0.45) | MEN1ALDH1A1KMT2AKEAP1 | |
| SCHEMBL286505 | 0.81 | FFAR1 (0.45) | MEN1ALDH1A1KMT2AKEAP1 | |
| SCHEMBL723768 | 0.80 | CXCL8 (0.56) | CXCL8AKR1B1TDP1PTGS2DUSP3 | |
| SCHEMBL2875381 | 0.80 | AKR1B1 (0.52) | CXCL8AKR1B1TDP1PTGS2ABCB11 | |
| SCHEMBL8645 | 0.79 | CXCL8 (0.65) | CXCL8AKR1B1TDP1PTGS2PTGS1 | |
| SCHEMBL29533621 | 0.79 | CXCL8 (0.65) | CXCL8AKR1B1TDP1PTGS2PTGS1 | |
| SCHEMBL25040843 | 0.78 | CXCL8 (0.42) | CXCL8AKR1B1TDP1CYP1A2 | |
| SCHEMBL1364609 | 0.78 | GABRA1 (0.68) | CXCL8AKR1B1TDP1PTGS2ABCB11 | |
| SCHEMBL30759635 | 0.78 | CXCL8 (0.42) | CXCL8AKR1B1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155873-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PHARMACEUTICS | 江苏恒瑞医药股份有限公司 | 2023-08-24 | — | — | WO | disclosed |