Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394039 | 1.00 | HTR6 (0.63) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL27038476 | 0.79 | HTR6 (0.64) | HTR6FABP4 | |
| SCHEMBL30644286 | 0.78 | HTR6 (0.68) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL260867 | 0.78 | HTR6 (0.68) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL30096985 | 0.78 | HTR6 (0.56) | HTR6PPARGPPARDPPARAHTR1A | |
| SCHEMBL505125 | 0.78 | HTR6 (0.56) | HTR6PPARGPPARDPPARAHTR1A | |
| SCHEMBL3625322 | 0.77 | FABP4 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL8499521 | 0.76 | HTR6 (0.53) | HTR6 | |
| SCHEMBL16923720 | 0.76 | PIK3C3 (0.46) | HTR6 | |
| SCHEMBL19278211 | 0.75 | HTR6 (0.43) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112673009-B | Substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-112771046-B | Other substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2023-09-19 | — | — | CN | disclosed |