Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 18/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 18/20 | 0.53 |
| ▸ | CDK9 | P50750 | 13/20 | 0.53 |
| ▸ | CCNK | O75909 | 12/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30560062 | 0.86 | ALK (0.53) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL23296218 | 0.78 | CDK6 (0.58) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL29684118 | 0.78 | CDK6 (0.58) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL20744489 | 0.78 | CCND3 (0.61) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL30560068 | 0.74 | PTK2 (0.52) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL19882691 | 0.74 | CCND3 (0.51) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL30560065 | 0.73 | SYK (0.55) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL16120652 | 0.70 | CDK6 (0.53) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL17709547 | 0.70 | CDK6 (0.53) | CCND3CDK6CDK9CCNKCCNA2 | |
| SCHEMBL30560067 | 0.70 | MAP4K1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733184-B1 | PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2023-08-30 | — | — | EP | claimed |