Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381894 | 1.00 | MAPT (0.66) | MAPTALDH1A1KDM4EATMKMT2A | |
| SCHEMBL23217100 | 0.86 | MAPT (0.70) | MAPTALDH1A1KDM4EATMKMT2A | |
| SCHEMBL31252083 | 0.86 | TRPV4 (0.58) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL25380430 | 0.83 | TRPV4 (0.55) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL30005546 | 0.81 | ALDH1A1 (0.64) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25380477 | 0.81 | GCK (0.59) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL31252072 | 0.81 | GCK (0.59) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL23217124 | 0.81 | PTPN11 (0.49) | MAPTALDH1A1KDM4EATMKMT2A | |
| SCHEMBL23217109 | 0.81 | NAMPT (0.47) | MAPTALDH1A1KDM4EATMKMT2A | |
| SCHEMBL23217375 | 0.80 | NAMPT (0.47) | MAPTALDH1A1KDM4EATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486453-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023166103-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | disclosed |