Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.84 |
| ▸ | MET | P08581 | 4/20 | 0.84 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.84 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.84 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.84 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.84 |
| ▸ | ABL1 | P00519 | 1/20 | 0.84 |
| ▸ | LCK | P06239 | 1/20 | 0.84 |
| ▸ | LYN | P07948 | 1/20 | 0.84 |
| ▸ | RET | P07949 | 1/20 | 0.84 |
| ▸ | HCK | P08631 | 1/20 | 0.84 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.84 |
| ▸ | BCR | P11274 | 1/20 | 0.84 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.84 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.84 |
| ▸ | FLT3 | P36888 | 1/20 | 0.84 |
| ▸ | ABL2 | P42684 | 1/20 | 0.84 |
| ▸ | FRK | P42685 | 1/20 | 0.84 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.84 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3061945 | 0.99 | KDR (0.82) | KDRMETMAPK14NTRK1EPHB6 | |
| Hydrochloric Acid SCHEMBL15452974 | 0.98 | KDR (0.81) | KDRMETMAPK14NTRK1EPHB6 | |
| SCHEMBL2250781 | 0.93 | KDR (0.89) | KDRMETMAPK14NTRK1EPHB6 | |
| Golvatinib SCHEMBL30498607 | 0.91 | MET (1.00) | KDRMETMAPK14NTRK1EPHB6 | |
| Golvatinib SCHEMBL30498608 | 0.91 | MET (1.00) | KDRMETMAPK14NTRK1EPHB6 | |
| Golvatinib SCHEMBL1727298 | 0.91 | MET (1.00) | KDRMETMAPK14NTRK1EPHB6 | |
| Golvatinib SCHEMBL4249254 | 0.90 | MET (0.99) | KDRMETMAPK14NTRK1EPHB6 | |
| Golvatinib SCHEMBL1727167 | 0.90 | MET (0.99) | KDRMETMAPK14NTRK1EPHB6 | |
| SCHEMBL14945014 | 0.90 | KDR (0.90) | KDRMETMAPK14NTRK1EPHB6 | |
| Golvatinib SCHEMBL1728754 | 0.89 | MET (0.92) | KDRMETMAPK14NTRK1EPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759530-B2 | Method for producing phenoxypyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-06-24 | — | — | US | disclosed |
| US-20140011999-A1 | Method for Producing Phenoxypyridine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| EP-2058302-B1 | METHOD FOR PRODUCING PHENOXYPYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2013-04-17 | — | — | EP | disclosed |
| US-8377938-B2 | Phenoxypyridine derivative salts and crystals thereof, and process for preparing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-7790885-B2 | Process for preparing phenoxypyridine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-7790885-B2 | Process for preparing phenoxypyridine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-7790885-B2 | Process for preparing phenoxypyridine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| EP-2058302-A1 | METHOD FOR PRODUCING PHENOXYPYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-20080318924-A1 | PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME | EISAI R&D MANAGEMENT CO., LTD (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080214815-A1 | Process for preparing phenoxypyridine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-04 | — | — | US | disclosed |
| US-20080214815-A1 | Process for preparing phenoxypyridine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-04 | — | — | US | disclosed |
| US-20080214815-A1 | Process for preparing phenoxypyridine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011999-A1 | Method for Producing Phenoxypyridine Derivative | QDPR, DRD4, DOT1L | KDR 1936/4885MET 263/4885MAPK14 1284/4885 |
| US-20080318924-A1 | PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME | HGF, MET, FLT1 | KDR 9/4885MET 2/4885MAPK14 946/4885 |
| US-20080214815-A1 | Process for preparing phenoxypyridine derivatives | FIP1L1, SKP1, TET2 | KDR 1759/4885MET 1938/4885MAPK14 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.