Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 9/20 | 0.39 |
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17477724 | 1.00 | TRPV4 (0.40) | TRPV4CTSSCTSKCTSBCTSL | |
| SCHEMBL25390806 | 0.87 | TRPV4 (0.42) | TRPV4SLC22A12 | |
| SCHEMBL15932451 | 0.86 | CTSS (0.40) | CTSSCTSKCTSBCTSLABCB1 | |
| SCHEMBL30570497 | 0.86 | CTSS (0.42) | CTSSCTSKCTSBCTSLABCB1 | |
| SCHEMBL17474200 | 0.86 | CTSS (0.42) | CTSSCTSKCTSBCTSLABCB1 | |
| SCHEMBL17476298 | 0.84 | KMT2A (0.40) | CTSSCTSKCTSBCTSLABCB1 | |
| SCHEMBL17474203 | 0.84 | CTSS (0.41) | CTSSCTSKCTSBCTSLABCB1 | |
| SCHEMBL10216722 | 0.84 | LMNA (0.44) | CTSSCTSKCTSBCTSLABCB1 | |
| SCHEMBL26227418 | 0.80 | CTSS (0.43) | CTSSCTSKCTSBCTSLAAK1 | |
| SCHEMBL17479521 | 0.80 | CTSS (0.38) | CTSSCTSKCTSBCTSLABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604308-B1 | SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2023-09-13 | — | — | EP | disclosed |