Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.43 |
| ▸ | CTSK | P43235 | 12/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504982 | 0.85 | CTSS (0.46) | CTSSCTSKCTSBCTSLAAK1 | |
| SCHEMBL21665877 | 0.84 | CTSS (0.43) | CTSSCTSKCTSBCTSL | |
| SCHEMBL20997615 | 0.82 | CTSS (0.41) | CTSSCTSKCTSBCTSL | |
| SCHEMBL17477724 | 0.80 | TRPV4 (0.40) | CTSSCTSKCTSBCTSLLMNA | |
| SCHEMBL30570520 | 0.80 | TRPV4 (0.40) | CTSSCTSKCTSBCTSLLMNA | |
| SCHEMBL20997532 | 0.80 | CTSS (0.44) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7995586 | 0.72 | CTSK (0.54) | CTSSCTSKCTSBCTSLLMNA | |
| SCHEMBL1725234 | 0.69 | LMNA (0.51) | LMNAPOLBAAK1 | |
| SCHEMBL24821266 | 0.69 | EPHX2 (0.46) | LMNAPOLBAAK1 | |
| SCHEMBL30392363 | 0.69 | EPHX2 (0.46) | LMNAPOLBAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604308-B1 | SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2023-09-13 | — | — | EP | disclosed |