Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | PNMT | P11086 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24203658 | 0.90 | TDP2 (0.38) | TDP2PARP1PARP10HTR2AHTR2C | |
| SCHEMBL30574140 | 0.83 | SLC6A3 (0.37) | TDP2SLC5A1SLC5A2 | |
| SCHEMBL3745692 | 0.81 | HTR2C (0.38) | TDP2PARP1PARP10SLC5A1SLC5A2 | |
| SCHEMBL11843801 | 0.79 | SLC6A2 (0.40) | — | |
| SCHEMBL30574127 | 0.79 | TDP2 (0.39) | TDP2PARP1PARP10 | |
| SCHEMBL8013342 | 0.75 | GRIN1 (0.50) | — | |
| SCHEMBL6350679 | 0.74 | SIGMAR1 (0.47) | — | |
| SCHEMBL30574142 | 0.73 | AVPR1A (0.39) | — | |
| SCHEMBL29190448 | 0.73 | TDP2 (0.38) | TDP2PNMT | |
| SCHEMBL31064604 | 0.72 | TDP2 (0.37) | TDP2PARP1PARP10HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640094-A | Compounds as PRMT1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |