Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.66 |
| ▸ | THRB | P10828 | 14/20 | 0.66 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003630 | 1.00 | THRA (0.66) | THRATHRBPLA2G10PLA2G2APTGDR2 | |
| SCHEMBL25399371 | 0.92 | THRB (0.65) | THRATHRBPTGDR2 | |
| SCHEMBL23003710 | 0.91 | THRA (0.59) | THRATHRBPLA2G10PLA2G2AFFAR1 | |
| SCHEMBL30574240 | 0.91 | THRA (0.61) | THRATHRBPLA2G10PLA2G2APTGDR2 | |
| SCHEMBL23003650 | 0.91 | THRA (0.61) | THRATHRBPLA2G10PLA2G2APTGDR2 | |
| SCHEMBL31350423 | 0.91 | THRA (0.55) | THRATHRBPLA2G10PLA2G2ABACE1 | |
| SCHEMBL25528706 | 0.91 | THRA (0.57) | THRATHRBPLA2G10PLA2G2AFFAR1 | |
| SCHEMBL25398092 | 0.91 | THRB (0.64) | THRATHRBPLA2G10PLA2G2APPARD | |
| SCHEMBL25398425 | 0.90 | THRB (0.62) | THRATHRBPLA2G10PLA2G2AFFAR1 | |
| SCHEMBL25397334 | 0.90 | THRB (0.62) | THRATHRBPLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177667-A1 | THYROID HORMONE RECEPTOR AGONISTS | BRII BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |