Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 18/20 | 0.62 |
| ▸ | THRA | P10827 | 16/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350368 | 0.90 | THRA (0.50) | THRBTHRA | |
| SCHEMBL30574232 | 0.90 | THRA (0.66) | THRBTHRAPLA2G10PLA2G2A | |
| SCHEMBL23003630 | 0.90 | THRA (0.66) | THRBTHRAPLA2G10PLA2G2A | |
| SCHEMBL25398618 | 0.89 | THRB (0.60) | THRBTHRAPLA2G10PLA2G2A | |
| SCHEMBL25398325 | 0.89 | THRB (0.60) | THRBTHRAPLA2G10PLA2G2A | |
| SCHEMBL25399371 | 0.88 | THRB (0.65) | THRBTHRA | |
| SCHEMBL31350400 | 0.88 | THRA (0.51) | THRBTHRA | |
| SCHEMBL30574229 | 0.88 | THRA (0.59) | THRBTHRAPLA2G10PLA2G2A | |
| SCHEMBL25399834 | 0.88 | THRA (0.59) | THRBTHRAPLA2G10PLA2G2A | |
| SCHEMBL25401057 | 0.88 | THRB (0.61) | THRBTHRAPLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177667-A1 | THYROID HORMONE RECEPTOR AGONISTS | BRII BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | WO | claimed |
| WO-2023177667-A1 | THYROID HORMONE RECEPTOR AGONISTS | BRII BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023177667-A1 | THYROID HORMONE RECEPTOR AGONISTS | BRII BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |