Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 8/20 | 0.58 |
| ▸ | JUN | P05412 | 7/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.58 |
| ▸ | RELA | Q04206 | 7/20 | 0.58 |
| ▸ | FOS | P01100 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATF1 | P18846 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131646 | 1.00 | NFKB1 (0.58) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL573798 | 0.87 | ALDH1A1 (0.54) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL423492 | 0.85 | JUN (0.60) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL4425453 | 0.84 | JUN (0.59) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL8543216 | 0.84 | KDM4E (0.72) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL28874828 | 0.84 | MAPT (0.44) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL3283794 | 0.83 | JUN (0.58) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL17393706 | 0.83 | JUN (0.58) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL12844275 | 0.83 | JUN (0.58) | NFKB1JUNNFKB2RELAFOS | |
| SCHEMBL12775469 | 0.82 | KDM4E (0.61) | NFKB1JUNNFKB2RELAFOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677716-A | Pharmaceutical compositions comprising WRN helicase inhibitors | 维维迪恩医疗公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-111356690-B | Benzamide derivative compound, preparation method thereof, and pharmaceutical composition for preventing or treating inflammatory disease | 首尔大学校产学协力团 | 2023-09-29 | — | — | CN | disclosed |