Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.53 |
| ▸ | WNT3A | P56704 | 4/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576086 | 0.91 | GSK3B (0.49) | MAPK10ALDH1A1SMN1; SMN2L3MBTL1RIOK2 | |
| SCHEMBL30576056 | 0.85 | F2 (0.49) | ALDH1A1GSK3ACDK2KDM4E | |
| SCHEMBL30576088 | 0.84 | CCNE2 (0.47) | CDK2 | |
| SCHEMBL30366861 | 0.82 | MAPT (0.58) | MAPK10SMN1; SMN2RIOK2WNT3AGSK3A | |
| SCHEMBL30366865 | 0.81 | RXRA (0.56) | MAPK10RIOK2GSK3ACDK2 | |
| SCHEMBL30576138 | 0.79 | NPC1 (0.51) | SMN1; SMN2CDK2 | |
| SCHEMBL30576069 | 0.78 | NPC1 (0.57) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30576128 | 0.77 | MAPT (0.55) | ALDH1A1GSK3ACDK2KDM4E | |
| SCHEMBL29083767 | 0.77 | RXRA (0.58) | ALDH1A1GSK3ACDK2KDM4E | |
| SCHEMBL30576104 | 0.77 | DYRK1A (0.54) | ALDH1A1GSK3ACDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |