Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576058 | 0.91 | RXRA (0.46) | GSK3AGSK3BSMONPC1RAB9A | |
| SCHEMBL30576056 | 0.87 | F2 (0.49) | GSK3AGSK3BNPC1RAB9AF2 | |
| SCHEMBL30576247 | 0.85 | DYRK1A (0.47) | GSK3BSMORAB9ASMN1; SMN2F10 | |
| SCHEMBL30576128 | 0.80 | MAPT (0.55) | GSK3AGSK3BNPC1RAB9AF2 | |
| SCHEMBL30576104 | 0.79 | DYRK1A (0.54) | GSK3AGSK3BNPC1RAB9AF2 | |
| SCHEMBL30576069 | 0.78 | NPC1 (0.57) | GSK3BNPC1RAB9AMAPTCYP2C19 | |
| SCHEMBL29083767 | 0.77 | RXRA (0.58) | GSK3AGSK3BNPC1RAB9AF2 | |
| SCHEMBL30576138 | 0.77 | NPC1 (0.51) | NPC1RAB9AMAPK14MAPTSMN1; SMN2 | |
| SCHEMBL30576180 | 0.77 | POLB (0.47) | GSK3AGSK3BNPC1RAB9AMAPK13 | |
| SCHEMBL30576105 | 0.75 | DYRK1A (0.60) | GSK3BNPC1RAB9AF2MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |