Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | WNT1 | P04628 | 5/20 | 0.53 |
| ▸ | GSK3B | P49841 | 4/20 | 0.53 |
| ▸ | CLK2 | P49760 | 3/20 | 0.52 |
| ▸ | CLK3 | P49761 | 3/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576143 | 0.89 | DYRK1A (0.54) | DYRK1ANPC1RAB9AWNT1GSK3B | |
| SCHEMBL30576175 | 0.89 | CHRM1 (0.55) | DYRK1ANPC1RAB9AWNT1GSK3B | |
| SCHEMBL30576056 | 0.88 | F2 (0.49) | DYRK1ANPC1RAB9AGSK3BF2 | |
| SCHEMBL30576128 | 0.88 | MAPT (0.55) | DYRK1ANPC1RAB9AGSK3BF2 | |
| SCHEMBL30576104 | 0.87 | DYRK1A (0.54) | DYRK1ANPC1RAB9AWNT1GSK3B | |
| SCHEMBL29083767 | 0.85 | RXRA (0.58) | DYRK1ANPC1RAB9AGSK3BF2 | |
| SCHEMBL30576045 | 0.80 | RXRA (0.46) | NPC1RAB9AGSK3BF2MAPK13 | |
| SCHEMBL30576069 | 0.78 | NPC1 (0.57) | DYRK1ANPC1RAB9AWNT1GSK3B | |
| SCHEMBL30576180 | 0.76 | POLB (0.47) | DYRK1ANPC1RAB9AWNT1GSK3B | |
| SCHEMBL30576121 | 0.76 | MAPK14 (0.52) | DYRK1ANPC1RAB9AWNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |