Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | WNT1 | P04628 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576105 | 0.89 | DYRK1A (0.60) | DYRK1AWNT1GSK3BMAPK14F2 | |
| SCHEMBL30576135 | 0.88 | DYRK1A (0.55) | CHRM1DYRK1AWNT1GSK3BMAPK14 | |
| SCHEMBL30576143 | 0.86 | DYRK1A (0.54) | DYRK1AWNT1GSK3BMAPK14F2 | |
| SCHEMBL30576056 | 0.85 | F2 (0.49) | DYRK1AGSK3BMAPK14F2KMT2A | |
| SCHEMBL30576128 | 0.85 | MAPT (0.55) | DYRK1AGSK3BMAPK14F2KMT2A | |
| SCHEMBL29083767 | 0.84 | RXRA (0.58) | DYRK1AGSK3BMAPK14F2KMT2A | |
| SCHEMBL30576104 | 0.84 | DYRK1A (0.54) | DYRK1AWNT1GSK3BMAPK14F2 | |
| SCHEMBL30576045 | 0.79 | RXRA (0.46) | GSK3BMAPK14F2KMT2ANPC1 | |
| SCHEMBL30576069 | 0.79 | NPC1 (0.57) | DYRK1AWNT1GSK3BKMT2APOLB | |
| SCHEMBL2072611 | 0.74 | SMN1; SMN2 (0.73) | CHRM1DYRK1AWNT1GSK3BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |