Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083767 | 0.89 | RXRA (0.58) | RXRAGSK3AGSK3BF2MAPK14 | |
| SCHEMBL30576128 | 0.82 | MAPT (0.55) | GSK3AGSK3BF2MAPK14MAPK13 | |
| SCHEMBL30576056 | 0.82 | F2 (0.49) | RXRAGSK3AGSK3BF2MAPK14 | |
| SCHEMBL30576104 | 0.81 | DYRK1A (0.54) | GSK3AGSK3BF2MAPK14MAPK13 | |
| SCHEMBL30576123 | 0.80 | MAPK14 (0.43) | RXRAGSK3BMAPK14PTGER4RAF1 | |
| SCHEMBL30576105 | 0.80 | DYRK1A (0.60) | GSK3BF2MAPK14MAPK13MAPK12 | |
| SCHEMBL30576175 | 0.79 | CHRM1 (0.55) | GSK3BF2MAPK14MAPK13MAPK12 | |
| SCHEMBL30576040 | 0.78 | PROKR1 (0.48) | GSK3AGSK3BMAPK14PROKR1NPC1 | |
| SCHEMBL30576143 | 0.78 | DYRK1A (0.54) | GSK3BF2MAPK14MAPK13MAPK12 | |
| SCHEMBL29083757 | 0.76 | RXRA (0.60) | RXRAGSK3AGSK3BMAPK14RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |