SCHEMBL305779

SCHEMBL305779

C=CC(N[Si](OC)(OC)OC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.35
MAPT P10636 4/20 0.35
CYP3A4 P08684 4/20 0.35
HSD17B10 Q99714 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 4/20 0.35
KDM4E B2RXH2 3/20 0.35
HPGD P15428 3/20 0.35
ALOX15 P16050 3/20 0.35
LMNA P02545 3/20 0.35
USP2 O75604 2/20 0.35
TP53 P04637 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALOX12 P18054 2/20 0.35
RAB9A P51151 1/20 0.32
TSHR P16473 3/20 0.32
CYP2D6 P10635 2/20 0.32
CHRM2 P08172 1/20 0.32
ADRA1A P35348 1/20 0.32
RGS12 O14924 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451843 0.78 AOC3 (0.34) KMT2AMAPTALDH1A1MEN1TSHR
Hydrochloric Acid SCHEMBL28487525 0.73 KMT2A (0.35) KMT2AMAPTCYP3A4HSD17B10ALDH1A1
SCHEMBL2028407 0.72 ALDH1A1 (0.46) KMT2AMAPTCYP3A4HSD17B10ALDH1A1
SCHEMBL9268820 0.72 SMN1; SMN2 (0.37) MAPTCYP3A4HSD17B10ALDH1A1KDM4E
SCHEMBL22551150 0.71 SIGMAR1 (0.34) KMT2AMAPTCYP3A4HSD17B10ALDH1A1
SCHEMBL26104988 0.71 LMNA (0.33) KMT2AMAPTCYP3A4HSD17B10ALDH1A1
SCHEMBL1453093 0.70 ALDH1A1 (0.38) KMT2AMAPTCYP3A4HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL21981229 0.70 SIGMAR1 (0.33) KMT2AMAPTCYP3A4HSD17B10ALDH1A1
SCHEMBL5361176 0.69 ALDH1A1 (0.37) MAPTCYP3A4HSD17B10ALDH1A1HPGD
Hydrochloric Acid SCHEMBL22362253 0.69 ALDH1A1 (0.40) KMT2AMAPTCYP3A4HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US claimed
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US claimed
EP-2173491-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2010-04-14 EP claimed
EP-2040847-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2009-04-01 EP claimed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO claimed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US claimed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO claimed
US-9567655-B2 Processes for the separation of ores GEORGIA-PACIFIC CHEMICALS LLC (US) 2017-02-14 US disclosed
US-9150666-B2 Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom ADA FOUNDATION (US) 2015-10-06 US disclosed
WO-2014066237-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-05-01 WO disclosed
US-20140110621-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-24 US disclosed
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US disclosed
US-8092686-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-01-10 US disclosed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO disclosed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US disclosed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO disclosed
EP-1838451-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC RESINS, INC. (US) 2007-10-03 EP disclosed
US-20070000839-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2007-01-04 US disclosed
US-20060151360-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2006-07-13 US disclosed
WO-2006071672-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2006-07-06 WO disclosed