Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | HPN | P05981 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30685475 | 0.71 | PLAT (0.40) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL30578687 | 0.71 | SMYD3 (0.44) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL29082309 | 0.71 | SMYD3 (0.44) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL30578666 | 0.69 | THRB (0.45) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL21801697 | 0.69 | RAB9A (0.51) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL5104085 | 0.68 | PARP1 (0.44) | NPC1ALDH1A1RAB9ASMN1; SMN2LOXL2 | |
| SCHEMBL30578681 | 0.68 | SMYD3 (0.41) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL21801541 | 0.67 | QPCT (0.47) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL21801540 | 0.64 | CDC7 (0.53) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL5100661 | 0.64 | PARP1 (0.43) | KDM4EMEN1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768877-A | ISR inhibitor and preparation method and application thereof | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |