Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 4/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578681 | 0.89 | SMYD3 (0.41) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL30578693 | 0.77 | ATF4 (0.51) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30685472 | 0.77 | RAB9A (0.41) | PLATALDH1A1NPC1RAB9AALOX15B | |
| SCHEMBL30578666 | 0.73 | THRB (0.45) | PLATALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL29082309 | 0.72 | SMYD3 (0.44) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL30578687 | 0.72 | SMYD3 (0.44) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL30578675 | 0.71 | KDM4E (0.40) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL30685471 | 0.70 | RAB9A (0.36) | NPC1CYP19A1RAB9AHPGD | |
| SCHEMBL21034692 | 0.67 | IDO1 (0.54) | ALDH1A1LMNACCNB2CDK1CCNB1 | |
| SCHEMBL21801697 | 0.66 | RAB9A (0.51) | ALDH1A1LMNAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023231948-A1 | ISR INHIBITORS, METHOD FOR PREPARING SAME, AND USE THEREOF | 中国药科大学 | 2023-12-07 | — | — | WO | disclosed |