Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468576 | 0.84 | — | — | |
| SCHEMBL938279 | 0.78 | XPO1 (0.37) | — | |
| SCHEMBL3485829 | 0.78 | PLK1 (0.31) | PTGS1 | |
| SCHEMBL1950924 | 0.77 | PKM (0.39) | MAOAMAOBALDH1A1MAPTMEN1 | |
| SCHEMBL6424333 | 0.68 | TYR (0.46) | TYRMAOAMAOBALDH1A1MAPT | |
| SCHEMBL6424546 | 0.67 | TYR (0.44) | TYRMAOAMAOBALDH1A1MAPT | |
| SCHEMBL6421978 | 0.65 | TYR (0.49) | TYRMAOAMAOBALDH1A1MAPT | |
| SCHEMBL14008639 | 0.65 | TYR (0.51) | TYRMAOAMAOBALDH1A1MAPT | |
| SCHEMBL14008598 | 0.63 | TYR (0.50) | TYRMAOAMAOBALDH1A1MAPT | |
| SCHEMBL8780706 | 0.63 | PKM (0.39) | MAOAMAOBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020101601-A2 | METHOD FOR PRODUCING CHEWING GUM USING PROPOLIS IN SOLID RESIN FORM | PALABIYIK IBRAHIM (TR) | 2020-05-22 | — | — | WO | disclosed |
| US-8487133-B2 | Substituted bicyclo [4.1.0] heptane-7-carboxylic acid amides and derivatives thereof as food flavor substances | SYMRISE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20100189863-A1 | SUBSTITUTED BICYCLO [4.1.0] HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO.KG (DE) | 2010-07-29 | — | — | US | disclosed |
| EP-2079322-A1 | SUBSTITUTED BICYCLOÝ4.1.0¨HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008046895-A1 | SUBSTITUTED BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189863-A1 | SUBSTITUTED BICYCLO [4.1.0] HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | HCAR3, TAS2R1, HCAR1 | TYR 645/4885MAOA 3177/4885MAOB 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.