SCHEMBL3485829

SCHEMBL3485829

O=C1C(=O)c2c(cc(O)c(O)c2O)OC1=C1C=CC=CC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15414521 0.84 TYR (0.40)
SCHEMBL3058448 0.78 TYR (0.40) PTGS1
SCHEMBL12468576 0.70
SCHEMBL1950924 0.69 PKM (0.39)
SCHEMBL938279 0.66 XPO1 (0.37)
SCHEMBL3513421 0.65 TYR (0.40)
SCHEMBL4470549 0.58 HKDC1 (0.39)
SCHEMBL3909589 0.57
SCHEMBL193801 0.57
SCHEMBL13090735 0.56 TYR (0.72)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100037355-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY CERES, INC (US) 2010-02-11 US disclosed
US-20060048240-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI 2006-03-02 US disclosed
EP-1546356-A2 EXTRACTION, PURIFICATION AND CONVERSION OF FLAVONOIDS FROM PLANT BIOMASS Her Majesty The Queen in Right of Canada, as represented by The Minister of Agriculture and Agri-Food (CA) 2005-06-29 EP disclosed
WO-2004027074-A2 EXTRACTION, PURIFICATION AND CONVERSION OF FLAVONOIDS FROM PLANT BIOMASS HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) 2004-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100037355-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY RNGTT, CPSF1, CPSF6 PLK1 3284/4885PTGS1 4544/4885PTGS2 4377/4885
US-20060048240-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 PLK1 3284/4885PTGS1 4544/4885PTGS2 4377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.