SCHEMBL30584818

SCHEMBL30584818

COc1ccc(-c2noc(N3CCN(C(=O)NCCCN4CCC(C(F)(F)F)CC4)CC3)n2)cc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ TSHR P16473 2/20 0.57
▸ LMNA P02545 6/20 0.55
▸ MAPT P10636 6/20 0.55
▸ HTT P42858 4/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ SMN1; SMN2 Q16637 4/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ POLB P06746 1/20 0.53
▸ TP53 P04637 5/20 0.52
▸ ALDH1A1 P00352 2/20 0.52
▸ GAA P10253 1/20 0.52
▸ THRB P10828 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584804 0.89 MEN1 (0.60) MEN1KMT2ATSHRLMNAMAPT
Formic Acid SCHEMBL30584933 0.87 TSHR (0.65) MEN1KMT2ATSHRLMNAMAPT
SCHEMBL31546418 0.85 LMNA (0.72) MEN1KMT2ATSHRLMNAMAPT
Formic Acid SCHEMBL30584798 0.83 MEN1 (0.56) MEN1KMT2ATSHRLMNAMAPT
SCHEMBL31667543 0.83 LMNA (0.58) MEN1KMT2ATSHRLMNAMAPT
SCHEMBL30584888 0.81 DRD2 (0.51) MEN1KMT2ATSHRLMNAMAPT
SCHEMBL31667398 0.80 LMNA (0.55) MEN1KMT2ATSHRLMNAMAPT
Formic Acid SCHEMBL31546410 0.80 LMNA (0.56) MEN1KMT2ATSHRLMNAMAPT
SCHEMBL30584958 0.80 MAPT (0.52) MEN1KMT2ATSHRLMNAMAPT
SCHEMBL31546336 0.79 MAPT (0.71) MEN1KMT2ALMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885TSHR 4347/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885TSHR 4347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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