SCHEMBL30584850

SCHEMBL30584850

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccccc5Cl)no4)CC3)C2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR5 P51681 1/20 0.54
▸ TP53 P04637 6/20 0.51
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ CHRM4 P08173 3/20 0.45
▸ THRB P10828 1/20 0.45
▸ MAPT P10636 2/20 0.44
▸ KCNH2 Q12809 1/20 0.44
▸ CACNA1I Q9P0X4 1/20 0.44
▸ RXFP1 Q9HBX9 1/20 0.44
▸ TUBB4A P04350 1/20 0.43
▸ TUBB P07437 1/20 0.43
▸ TUBA3C P0DPH7 1/20 0.43
▸ TUBA1B P68363 1/20 0.43
▸ TUBA4A P68366 1/20 0.43
▸ TUBB4B P68371 1/20 0.43
▸ TUBB3 Q13509 1/20 0.43
▸ TUBB2A Q13885 1/20 0.43
▸ TUBB8 Q3ZCM7 1/20 0.43
▸ TUBA3E Q6PEY2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546396 0.94 CCR5 (0.54) CCR5TP53MEN1KMT2ACHRM4
SCHEMBL30584799 0.91 CCR5 (0.52) CCR5TP53CHRM4MAPT
SCHEMBL31546362 0.86 CCR5 (0.54) CCR5TP53MEN1KMT2ACHRM4
Formic Acid SCHEMBL25432702 0.86 CCR5 (0.46) CCR5TP53MEN1KMT2ACHRM4
SCHEMBL25433137 0.86 CCR5 (0.53) CCR5TP53MEN1KMT2AMAPT
SCHEMBL25434022 0.85 CCR5 (0.52) CCR5TP53MEN1KMT2ACHRM4
SCHEMBL30584795 0.85 CCR5 (0.52) CCR5TP53MEN1KMT2ACHRM4
SCHEMBL31546339 0.84 CCR5 (0.50) CCR5TP53MEN1KMT2AMAPT
SCHEMBL25437981 0.84 LMNA (0.59) CCR5MEN1KMT2AMAPT
Formic Acid SCHEMBL25433807 0.84 CCR5 (0.50) CCR5TP53MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 CCR5 3713/4885TP53 54/4885MEN1 1569/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CCR5 3713/4885TP53 54/4885MEN1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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