SCHEMBL31546396

SCHEMBL31546396

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccccc5C)no4)CC3)C2)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CCR5 P51681 1/20 0.54
▸ TP53 P04637 6/20 0.51
▸ THRB P10828 1/20 0.51
▸ MAPT P10636 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ CHRM4 P08173 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ RXFP1 Q9HBX9 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ SCN4A P35499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584850 0.94 CCR5 (0.54) CCR5TP53THRBMAPTCHRM4
SCHEMBL30584799 0.91 CCR5 (0.52) CCR5TP53MAPTCHRM4LMNA
SCHEMBL31546362 0.86 CCR5 (0.54) CCR5TP53THRBMAPTSMN1; SMN2
SCHEMBL25433137 0.86 CCR5 (0.53) CCR5TP53MAPTSMN1; SMN2LMNA
SCHEMBL25434022 0.85 CCR5 (0.52) CCR5TP53THRBMAPTCHRM4
SCHEMBL30584795 0.85 CCR5 (0.52) CCR5TP53THRBMAPTCHRM4
SCHEMBL31546339 0.84 CCR5 (0.50) CCR5TP53MAPTSMN1; SMN2LMNA
SCHEMBL25437981 0.84 LMNA (0.59) CCR5MAPTSMN1; SMN2LMNAPOLB
SCHEMBL30584749 0.83 LMNA (0.53) CCR5TP53MAPTLMNAMEN1
SCHEMBL30584823 0.83 ACHE (0.51) CCR5TP53MAPTCHRM4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 CCR5 3713/4885TP53 54/4885THRB 2458/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CCR5 3713/4885TP53 54/4885THRB 2458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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