SCHEMBL30584823

SCHEMBL30584823

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccc(C#N)cc5)no4)CC3)C2)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 0.51
▸ CCR5 P51681 1/20 0.51
▸ MAPT P10636 3/20 0.49
▸ CHRM4 P08173 3/20 0.46
▸ LMNA P02545 3/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ TP53 P04637 2/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30585036 0.91 MAPT (0.52) ACHECCR5MAPTCHRM4LMNA
SCHEMBL25433137 0.91 CCR5 (0.53) CCR5MAPTLMNAMEN1KMT2A
SCHEMBL30584763 0.90 MAPT (0.45) ACHECCR5MAPTCHRM4LMNA
SCHEMBL25437981 0.88 LMNA (0.59) CCR5MAPTLMNAMEN1KMT2A
SCHEMBL30584949 0.88 MEN1 (0.49) CCR5MAPTLMNAMEN1KMT2A
SCHEMBL30584749 0.88 LMNA (0.53) CCR5MAPTLMNAMEN1KMT2A
SCHEMBL31546464 0.87 RXFP3 (0.51) ACHEMAPTLMNAMEN1KMT2A
SCHEMBL30584714 0.86 CCR5 (0.48) CCR5MAPTLMNAMEN1KMT2A
SCHEMBL31546362 0.86 CCR5 (0.54) CCR5MAPTCHRM4LMNAMEN1
SCHEMBL31546461 0.85 LMNA (0.57) MAPTLMNAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 ACHE 4880/4885CCR5 3713/4885MAPT 2999/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 ACHE 4880/4885CCR5 3713/4885MAPT 2999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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