Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.39 |
| ▸ | THRB | P10828 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586150 | 0.92 | THRA (0.38) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29134012 | 0.86 | THRA (0.51) | THRATHRBCYP2C9PDE9A | |
| SCHEMBL30586152 | 0.84 | THRB (0.46) | THRATHRBPDE9A | |
| SCHEMBL30586144 | 0.81 | THRA (0.35) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29134029 | 0.80 | THRA (0.52) | THRATHRBCYP2C9 | |
| SCHEMBL30586153 | 0.80 | THRA (0.36) | THRATHRB | |
| SCHEMBL30586137 | 0.79 | THRA (0.35) | THRATHRB | |
| SCHEMBL30586140 | 0.79 | THRA (0.35) | THRATHRB | |
| SCHEMBL29134021 | 0.79 | THRA (0.52) | THRATHRBCYP2C9 | |
| SCHEMBL30586146 | 0.78 | THRB (0.46) | THRATHRBCYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836158-A | Compound serving as thyroid hormone beta receptor agonist and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |