Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.46 |
| ▸ | THRA | P10827 | 5/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586151 | 0.92 | THRB (0.46) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL30586162 | 0.91 | P2RX7 (0.45) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL30586155 | 0.84 | THRA (0.39) | THRBTHRAPDE9A | |
| SCHEMBL29134012 | 0.82 | THRA (0.51) | THRBTHRAPDE9A | |
| SCHEMBL30586149 | 0.81 | P2RX7 (0.38) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL30586141 | 0.80 | P2RX7 (0.39) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL30586138 | 0.77 | THRB (0.55) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL30586144 | 0.76 | THRA (0.35) | THRBTHRA | |
| SCHEMBL29134029 | 0.76 | THRA (0.52) | THRBTHRA | |
| SCHEMBL30586150 | 0.76 | THRA (0.38) | THRBTHRAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836158-A | Compound serving as thyroid hormone beta receptor agonist and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |