Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 12/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035943 | 0.89 | MEN1 (0.67) | CHRNA7TRPV1MEN1KMT2AHPGD | |
| SCHEMBL31036052 | 0.86 | MTNR1A (0.52) | CHRNA7TRPV1GAAMTNR1AMTNR1B | |
| SCHEMBL23928858 | 0.85 | CHRNA7 (0.64) | CHRNA7TRPV1KDM4E | |
| SCHEMBL23928856 | 0.79 | CHRNA7 (0.57) | CHRNA7TRPV1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL30587447 | 0.79 | CHRNA7 (0.57) | CHRNA7TRPV1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL31369499 | 0.77 | CHRNA7 (0.52) | CHRNA7TRPV1KDM4E | |
| SCHEMBL1253366 | 0.77 | CHRNA7 (0.50) | CHRNA7TRPV1 | |
| SCHEMBL31035952 | 0.77 | NOTUM (0.62) | CHRNA7MEN1KMT2AHPGDKDM4E | |
| SCHEMBL9373216 | 0.76 | HPGD (0.55) | CHRNA7TRPV1MEN1KMT2AHPGD | |
| SCHEMBL31036025 | 0.76 | HPGD (0.53) | CHRNA7TRPV1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |