Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889133 | 1.00 | TSPO (0.52) | TSPONR1I2ABCB11ALBADORA3 | |
| Hydrochloric Acid SCHEMBL14889244 | 0.99 | TSPO (0.51) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL30589252 | 0.94 | TSPO (0.45) | TSPOALBOPRK1KCNH2GABRA2 | |
| SCHEMBL14889211 | 0.94 | TSPO (0.45) | TSPOALBOPRK1KCNH2GABRA2 | |
| Hydrochloric Acid SCHEMBL14889118 | 0.93 | TSPO (0.44) | TSPOALBOPRK1KCNH2GABRA2 | |
| SCHEMBL14899704 | 0.92 | TSPO (0.44) | TSPOGABRA2GABRB2 | |
| SCHEMBL15158408 | 0.92 | TSPO (0.47) | TSPO | |
| Hydrochloric Acid SCHEMBL14889138 | 0.91 | TSPO (0.43) | TSPOGABRA2GABRB2 | |
| Hydrochloric Acid SCHEMBL14889126 | 0.91 | TSPO (0.46) | TSPO | |
| SCHEMBL12071924 | 0.89 | TSPO (0.55) | TSPONR1I2ABCB11ALBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293537-A1 | USE OF ACETAMIDE DERIVATIVE IN PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-21 | — | — | US | claimed |
| US-20230293537-A1 | USE OF ACETAMIDE DERIVATIVE IN PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293537-A1 | USE OF ACETAMIDE DERIVATIVE IN PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE | ACHE, APP, NAAA | TSPO 1344/4885NR1I2 1357/4885ABCB11 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.