Sugi Predict

Sugi Predict / Compounds / SCHEMBL30593545

SCHEMBL30593545

SCHEMBL30593545

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(N)=O)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.63
▸ KDM1A O60341 2/20 0.58
▸ NMUR2 Q9GZQ4 3/20 0.58
▸ NMUR1 Q9HB89 3/20 0.58
▸ NPY2R P49146 6/20 0.58
▸ NPY4R P50391 6/20 0.58
▸ NPY5R Q15761 6/20 0.58
▸ NPY1R P25929 4/20 0.58
▸ AGTR2 P50052 3/20 0.58
▸ AGTR1 P30556 2/20 0.58
▸ EP300 Q09472 1/20 0.58
▸ HIF1A Q16665 1/20 0.58
▸ F2 P00734 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30880904 0.90 EPHA2 (0.59) EPHA2KDM1ANPY2RNPY4RNPY5R
SCHEMBL30495807 0.90 NPY2R (0.62) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30883233 0.89 NMUR2 (0.68) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL29514899 0.89 KDM1A (0.66) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30712908 0.89 KDM1A (0.62) KDM1ANMUR2NMUR1NPY2RNPY4R
SCHEMBL29514978 0.88 KDM1A (0.64) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL31091491 0.88 EPHA2 (0.61) EPHA2KDM1ANMUR2NMUR1NPY2R
SCHEMBL29410236 0.88 MAPK8 (0.59) EPHA2KDM1ANMUR2NMUR1NPY2R
SCHEMBL31020752 0.88 NPY2R (0.64) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL30804676 0.87 NPY2R (0.63) EPHA2KDM1ANPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4511364-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES Suntec Medical, Inc. (US) 2025-02-26 — — EP claimed
CN-119403795-A Methods for treating central nervous system disorders 欣扬生医股份有限公司 2025-02-07 — — CN claimed
US-20250041218-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES SUNTEC MEDICAL INC (US) 2025-02-06 — — US claimed
WO-2023205171-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES SUNTEC MEDICAL, INC. (US) 2023-10-26 — — WO claimed
EP-4536209-A2 CONJUGATE FOR TARGETING CENTRAL NERVOUS SYSTEM Suntec Medical, Inc. (US) 2025-04-16 — — EP disclosed
CN-119744169-A Conjugates for targeting the central nervous system 欣扬生医股份有限公司 2025-04-01 — — CN disclosed
US-20250090673-A1 CONJUGATE FOR TARGETING CENTRAL NERVOUS SYSTEM SUNTEC MEDICAL INC (US) 2025-03-20 — — US disclosed
EP-4511364-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES Suntec Medical, Inc. (US) 2025-02-26 — — EP disclosed
CN-119403795-A Methods for treating central nervous system disorders 欣扬生医股份有限公司 2025-02-07 — — CN disclosed
US-20250041218-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES SUNTEC MEDICAL INC (US) 2025-02-06 — — US disclosed
WO-2023205171-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES SUNTEC MEDICAL, INC. (US) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041218-A1 METHOD FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES PMP22, KEAP1, APOB EPHA2 53/4885KDM1A 3503/4885NMUR2 635/4885
US-20250090673-A1 CONJUGATE FOR TARGETING CENTRAL NERVOUS SYSTEM PYGB, PMP22, GMFG EPHA2 21/4885KDM1A 3045/4885NMUR2 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback