Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595861 | 1.00 | USP2 (0.49) | USP2CYP3A4RENALDH1A1CYP2C9 | |
| SCHEMBL28324288 | 0.86 | TSHR (0.59) | USP2CYP3A4ALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL31112011 | 0.84 | MLNR (0.50) | USP2CYP3A4RENALDH1A1CYP2C9 | |
| SCHEMBL28786999 | 0.82 | LMNA (0.53) | RENCYP2C9MGLLCYP1A2EPHX1 | |
| SCHEMBL21650810 | 0.82 | FAAH (0.59) | USP2CYP3A4ALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL4599565 | 0.82 | EPHX1 (0.68) | CYP2C9SMN1; SMN2FAAHCYP1A2EPHX1 | |
| SCHEMBL30595900 | 0.82 | ADRB1 (0.55) | MGLLEPHX1HSD17B10TSHR | |
| SCHEMBL27627256 | 0.81 | ALOX15 (0.56) | ALDH1A1CYP2C9SMN1; SMN2HTR1ASLC6A2 | |
| SCHEMBL2583030 | 0.81 | GAA (0.61) | USP2CYP3A4ALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL30865723 | 0.77 | TRPV1 (0.46) | USP2CYP3A4ALDH1A1CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |