Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596239 | 0.85 | ALOX5 (0.56) | MAPK14ALOX5MGLLKDM4EALDH1A1 | |
| SCHEMBL2978602 | 0.78 | ALOX5 (0.50) | MAPK14ALOX5MGLLKDM4EALDH1A1 | |
| SCHEMBL11226834 | 0.78 | ALOX5 (0.53) | MAPK14ALOX5MGLLKDM4EALDH1A1 | |
| SCHEMBL28459546 | 0.76 | MGLL (0.45) | MAPK14MGLLAADATKDM4EALDH1A1 | |
| SCHEMBL32677307 | 0.75 | MEN1 (0.47) | MGLLALDH1A1GAA | |
| SCHEMBL22631177 | 0.69 | AADAT (0.58) | AADATKDM4EALDH1A1GAA | |
| SCHEMBL17974970 | 0.67 | MEN1 (0.49) | AADATKDM4EALDH1A1GAA | |
| SCHEMBL30363357 | 0.67 | AADAT (0.43) | AADATKDM4EALDH1A1GAA | |
| SCHEMBL11409331 | 0.66 | CES1 (0.58) | MAPK14MGLLALDH1A1GAA | |
| SCHEMBL30596240 | 0.66 | CES1 (0.58) | MAPK14MGLLALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836102-A | Method for preparing sodium diclofenac chloro impurity (3-chloro-N- (2, 6-dichlorophenyl) indol-2-one) | 河南东泰制药有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116836102-A | Method for preparing sodium diclofenac chloro impurity (3-chloro-N- (2, 6-dichlorophenyl) indol-2-one) | 河南东泰制药有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116836102-A | Method for preparing sodium diclofenac chloro impurity (3-chloro-N- (2, 6-dichlorophenyl) indol-2-one) | 河南东泰制药有限公司 | 2023-10-03 | — | — | CN | disclosed |