Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087309 | 1.00 | HTR3A (0.57) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL29994839 | 0.79 | DRD2 (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL17376186 | 0.79 | DRD2 (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL17376328 | 0.78 | MAPT (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL21725457 | 0.77 | PIM1 (0.47) | HTR3AALDH1A1PIM1PIM3PIM2 | |
| SCHEMBL3973534 | 0.76 | HTR3E (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL16146289 | 0.76 | HTT (0.57) | HTR3AALDH1A1PIM1PIM3PIM2 | |
| SCHEMBL31669179 | 0.76 | HTT (0.57) | HTR3AALDH1A1PIM1PIM3PIM2 | |
| SCHEMBL31318672 | 0.75 | ALDH1A1 (0.43) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5395255 | 0.75 | NR4A1 (0.49) | ALDH1A1SMPD3SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |