Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3155487 | 0.89 | OPRM1 (0.55) | OPRM1OPRL1OPRK1OPRD1CYP2C9 | |
| SCHEMBL5486179 | 0.85 | OPRK1 (0.49) | OPRM1OPRL1OPRK1OPRD1CYP2C9 | |
| SCHEMBL29087351 | 0.81 | OPRM1 (0.52) | OPRM1OPRL1OPRK1OPRD1KCNH2 | |
| SCHEMBL30057981 | 0.78 | GRM6 (0.55) | OPRM1OPRK1OPRD1KCNH2CHRM2 | |
| SCHEMBL11545110 | 0.78 | CHRM2 (0.47) | OPRM1OPRK1OPRD1KCNH2CHRM2 | |
| SCHEMBL1513400 | 0.78 | DRD2 (0.62) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11545113 | 0.78 | CHRM2 (0.47) | OPRM1OPRK1OPRD1KCNH2CHRM2 | |
| SCHEMBL1843594 | 0.76 | OPRK1 (0.61) | OPRM1OPRK1OPRD1KCNH2 | |
| SCHEMBL1843593 | 0.76 | OPRK1 (0.61) | OPRM1OPRK1OPRD1KCNH2 | |
| SCHEMBL7290091 | 0.74 | CHRM2 (0.46) | OPRM1OPRK1OPRD1KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |